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	Provedor de dados BJMBR (2) Autor Huang,L. (2) Chang,J.L. (1) Jing,R. (1) Kuang,F. (1) Li,J.L. (1) Liu,G.C. (1) Liu,X. (1) Long,T.Y. (1) Qian,Z.X. (1) Yang,T.L. (1) Yu,X.F. (1) Zhang,W.Y. (1) Mais... Palavra-chave CIRBP (1) Cell apoptosis (1) Cell proliferation (1) Circulating strain (1) Coxsackievirus A16 (1) Myocardial ischemia (1) NF-κB (1) Non-circulating strain (1) Pathogenicity (1) Mais... Tipo do documento Info:eu-repo/semantics/article (2) Ano 2017 (1) 2015 (1) País Brazil (2) Idioma Inglês (2)		Ordenar por:  Relevância Autor Título Ano Registros recuperados: 2 Primeira ... 1 ... Última CIRBP protects H9C2 cells against myocardial ischemia through inhibition of NF-κB pathway BJMBR Long,T.Y.; Jing,R.; Kuang,F.; Huang,L.; Qian,Z.X.; Yang,T.L.. Myocardial ischemia is a major cause of death and remains a disease with extremely deficient clinical therapies and a major problem worldwide. Cold inducible RNA-binding protein (CIRBP) is reported to be involved in multiple pathological processes, including myocardial ischemia. However, the molecular mechanisms of myocardial ischemia remain elusive. Here, we first overexpressed CIRBP by transfection of pc-CIRBP (pcDNA3.1 containing coding sequenced for CIRBP) and silenced CIRBP by transfection of small interfering RNA targeting CIRBP (siCIRBP). pcDNA3.1 and the negative control of siCIRBP (siNC) were transfected into H9C2 cells to act as controls. We then constructed a cell model of myocardial ischemia through culturing cells in serum-free medium with... Tipo: Info:eu-repo/semantics/article Palavras-chave: Myocardial ischemia; CIRBP; NF-κB; Cell proliferation; Cell apoptosis. Ano: 2017 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2017000400602 Comparative pathogenicity of Coxsackievirus A16 circulating and noncirculating strains in vitro and in a neonatal mouse model BJMBR Huang,L.; Liu,X.; Li,J.L.; Chang,J.L.; Liu,G.C.; Yu,X.F.; Zhang,W.Y.. An enterovirus 71 (EV71) vaccine for the prevention of hand, foot, and mouth disease (HMFD) is available, but it is not known whether the EV71 vaccine cross-protects against Coxsackievirus (CV) infection. Furthermore, although an inactivated circulating CVA16 Changchun 024 (CC024) strain vaccine candidate is effective in newborn mice, the CC024 strain causes severe lesions in muscle and lung tissues. Therefore, an effective CV vaccine with improved pathogenic safety is needed. The aim of this study was to evaluate the in vivo safety and in vitro replication capability of a noncirculating CVA16 SHZH05 strain. The replication capacity of circulating CVA16 strains CC024, CC045, CC090 and CC163 and the noncirculating SHZH05 strain was evaluated by cytopathic... Tipo: Info:eu-repo/semantics/article Palavras-chave: Coxsackievirus A16; Pathogenicity; Circulating strain; Non-circulating strain. Ano: 2015 URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2015000500420 Registros recuperados: 2 Primeira ... 1 ... Última

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